Missouri’s 12 Finest Wineries to Savor & Indulge

Missouri might not always be the first destination that comes to mind for wine lovers, but it should be. With its rolling hills, river bluffs, and deep-rooted viticultural history, the state offers more than just scenery—it delivers some of the best wineries in Missouri. 

From historic cellars to contemporary tasting rooms with panoramic views, each winery on this list offers something exceptional.

In fact, some of the locations we’ll highlight are often listed among the top destinations in Missouri that everyone should visit.

Whether you’re planning a leisurely weekend getaway or building a wine trail itinerary, you’ll find a rich tapestry of flavors, stories, and landscapes in Missouri’s thriving wine country.

1. Stone Hill Winery – Hermann

Start your journey at one of Missouri’s most iconic wineries. Stone Hill, founded in 1847, was once the second-largest winery in the US. Today, its restored cellars and carefully crafted Norton and Vignoles wines tell the story of a proud legacy reborn.

Take the cellar tour, relax in the wine garden, or enjoy a meal at the on-site Vintage 1847 Restaurant. It’s classic Missouri hospitality at its finest.

2. Augusta Winery – Augusta

Situated in America’s very first AVA, Augusta Winery is a must-visit for its focus on terroir-driven wines. 

This boutique operation crafts small-batch vintages that capture the character of the Missouri River Valley. Their shaded patio offers a quiet place to sip award-winning Chambourcin while watching the afternoon fade.

3. Les Bourgeois Vineyards – Rocheport

High on the bluff above the Missouri River, Les Bourgeois offers more than a great wine list—it delivers unforgettable views. 

Their A-Frame Winegarden and Blufftop Bistro are local favorites for sunset dinners and casual wine flights. Sample their Riverboat Red or try their Dry Vignoles with a charcuterie board.

4. St. James Winery – St. James

If you’re after variety, head to St. James. As one of the state’s largest producers, they offer a vast portfolio—from dry whites to dessert wines and fruit blends. 

Their innovation goes hand-in-hand with sustainable vineyard practices. The Winegarden here is perfect for laid-back afternoons and live music events.

5. Adam Puchta Winery – Hermann

Just outside Hermann’s historic downtown, Adam Puchta Winery holds the title of the oldest continuously owned family winery in the country. 

The atmosphere is rustic and inviting, with scenic grounds that practically beg for a picnic. Their Norton Reserve and Chardonnay are standout pours.

6. Chandler Hill Vineyards – Defiance

Looking for sophistication without pretense? Chandler Hill marries rustic charm with upscale ambiance. 

The property overlooks rolling vineyards and features a stylish tasting room with an expansive deck.

Their menu includes estate wines and select imports from Napa and Oregon, giving you a global tasting experience right in Missouri.

7. Montelle Winery – Augusta

Montelle offers a full sensory experience. Not only can you enjoy stellar wines like Seyval Blanc and Chambourcin, but the winery’s on-site café serves up delicious pairings. 

Located on a high ridge, the views are exceptional, especially during the fall foliage season.

8. Pirtle Winery – Weston

Housed in a former Lutheran Evangelical church from the 1800s, Pirtle Winery brings history and wine together in a unique and atmospheric way. 

Their range includes both traditional grape varietals and honey wines (mead), which add a unique twist to the tasting. Don’t miss their rooftop vine-covered wine garden in spring.

9. Noboleis Vineyards – Augusta

This family-owned gem sits atop some of Augusta’s prettiest hills. Noboleis combines laid-back hospitality with quality wines and a scenic hilltop pavilion that frequently hosts music events and local food trucks.

Grab a bottle of Vidal Blanc or Chambourcin and stay awhile.

10. Seven Springs Winery – Linn Creek

Located between Osage Beach and Camdenton near the Lake of the Ozarks, Seven Springs offers an inviting environment complete with live music, patio seating, and a full menu of house-made snacks and meals. 

The wine list includes both dry and sweet options, ensuring there's something for everyone.

11. TerraVox – Weston

TerraVox is anything but traditional. Focused on reviving rare American grape varietals, this winery explores forgotten possibilities of viticulture. 

You won’t find Chardonnay or Merlot here—instead, you’ll taste unique offerings like Lomanto or Cloeta. 

It’s an adventurous, thoughtful wine experience for those eager to discover something different.

12. Vox Vineyards – Kansas City

An extension of TerraVox, Vox Vineyards focuses on biodiversity and preserving rare grapes native to North America. Located just outside Kansas City, the wines here are both a conversation and a celebration. 

Don’t be surprised if a tasting turns into a philosophical chat about the future of winemaking.

Savor the Heart of Missouri Wine Country

The best wineries in Missouri aren’t just places to drink wine—they’re destinations rich in story, tradition, and innovation. Each one reflects the local terrain, climate, and personality of its winemakers. 

Whether you're exploring the historic charm of Hermann, the trailblazing fields near Kansas City, or the river bluffs of Augusta, you’ll find a mosaic of flavors that’s distinctively Missouri.

You’ll also notice how many of these wineries are connected—family-owned, generational, and passionately committed to the craft. They welcome you in, pour generously, and invite you to stay a while. That’s the heart of Missouri’s wine scene.

Stay Where Comfort Meets Charm

A visit to the best wineries in Missouri deserves a stay that reflects the same elegance and local pride. That’s where River Sirens Hotel comes in.

Located just a short drive from some of the region’s finest wineries, River Sirens offers boutique accommodation in Washington, MO, with stunning river views, curated interiors, and thoughtful touches that make your stay feel both refined and personal. 

It’s the perfect home base for your wine country escape—whether you're toasting a special occasion or simply treating yourself to something memorable.

Book Your Stay at River Sirens Hotel

After a day spent exploring the best wineries in Missouri, retreat to comfort, style, and serenity at River Sirens Hotel. Enjoy walkable access to local dining, riverfront views, and bespoke accommodations that echo the charm of Missouri wine country.

Book your stay today and elevate your next getaway—because every perfect pour deserves a perfect night’s rest.